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1

Studies on the Synthesis and Opioid Agonistic Activities of Mitragynine-Related Indole Alkaloids: Discovery of Opioid Agonists Structurally Different from Other Opioid Ligands

Takayama, Hiromitsu, Ishikawa, Hayato, Kurihara, Mika, Kitajima, Mariko, Aimi, Norio, Ponglux, Dhavadee, Koyama, Fumi, Matsumoto, Kenjiro, Moriyama, Tomoyuki, Yamamoto, Leonard T., Watanabe, Kazuo, Mu

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 125 KB

english, 2002

2

Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa

Leonardo T. Yamamoto, Syunji Horie, Hiromitsu Takayama, Norio Aimi, Shin-ichiro Sakai, Shingo Yano, Jie Shan, Peter K.T. Pang, Dhavadee Ponglux, Kazuo Watanabe

Journal:

General Pharmacology: The Vascular System

Year:

1999

Language:

english

File:

PDF, 146 KB

english, 1999

3

A New Indole Alkaloid, 7 α-Hydroxy-7 H -mitragynine, from Mitragyna speciosa in Thailand

Ponglux, Dhavadee, Wongseripipatana, Sumphan, Takayama, Hiromitsu, Kikuchi, Masae, Kurihara, Mika, Kitajima, Mariko, Aimi, Norio, Sakai, Shin-ichiro

Journal:

Year:

1994

Language:

english

File:

PDF, 204 KB

english, 1994

4

Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa

Kenjiro Matsumoto, Syunji Horie, Hiromitsu Takayama, Hayato Ishikawa, Norio Aimi, Dhavadee Ponglux, Toshihiko Murayama, Kazuo Watanabe

Journal:

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

5

Inhibitory effect of mitragynine, an analgesic alkaloid from Thai herbal medicine, on neurogenic contraction of the vas deferens

Kenjiro Matsumoto, Leonardo T. Yamamoto, Kazuo Watanabe, Shingo Yano, Jie Shan, Peter K.T. Pang, Dhavadee Ponglux, Hiromitsu Takayama, Syunji Horie

Journal:

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

6

Alkaloids of Uncaria attenuata from Thailand

Dhavadee Ponglux, Tanomjit Supavita, Robert Verpoorte, David Phillipson

Journal:

Year:

1980

Language:

english

File:

PDF, 418 KB

english, 1980

7

Triterpenoidal constituents of uncaria florida vidal

Norio Aimi, Kittisak Likhitwitayawuid, Junko Goto, Dhavadee Ponglux, Joju Haginiwa, Shin-ichiro Sakai

Journal:

Year:

1989

Language:

english

File:

PDF, 648 KB

english, 1989

8

Studies on the indole alkaloids of gelsem1um elegans (thailand): structure elucidation and proposal of biogenetic route

Dhavadee Ponglux, Sumphan Wongseripipatana, Sanan Subhadhirasakul, Hiromitsu Takayama, Masaki Yokota, Koreharu Ogata, Chada Phisalaphong, Norio Aimi, Shin-ichiro Sakai

Journal:

Year:

1988

Language:

english

File:

PDF, 1.36 MB

english, 1988

9

A new class of indole alkaloid ‘elegansamine’ constructed from a monoterpenoid indole alkaloid and an iridoid

Dhavadee Ponglux, Sumphan Wongseripipatana, Hiromitsu Takayama, Koreharu Ogata, Norio Aimi, Shin-ichiro Sakai

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 146 KB

english, 1988

10

Biomimetic synthesis of koumine skeleton: Partial synthesis of 11-methoxykoumine ( gelsemium-type alkaloid ) from 18-hydroxygardnerine

Shin-ichiro Sakal, Etsuji Yamanaka, Mariko Kitajima, Masaki Yokota, Norio Aimi, Sumphan Wongseripatana, Dhavadee Ponglux

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 208 KB

english, 1986

11

Alkaloids of kopsia jasminiflora from Thailand

Nijsiri Ruangrungsi, Kittisak Likhitwitayawuid, Vichien Jongbunprasert, Dhavadee Ponglux, Norio Aimi, Koreharu Ogata, Megumi Yasuoka, Joju Haginiwa, Shin-ichiro Sakai

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 259 KB

english, 1987

12

Introduction of hydroxyl group at C-14 of indole alkaloids: the partial synthesis of 14α-hydroxyrauniticine

Etsuji Yamanaka, Etsuko Maruta, Satoe Kasamatsu, Norio Aimi, Shin-ichiro Sakai, Dhavadee Ponglux, Sumphan Wongseripipatana, Tanomjit Supavita

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 230 KB

english, 1983

13

Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa

Kenjiro Matsumoto, Syunji Horie, Hayato Ishikawa, Hiromitsu Takayama, Norio Aimi, Dhavadee Ponglux, Kazuo Watanabe

Journal:

Year:

2004

Language:

english

File:

PDF, 196 KB

english, 2004

14

Partial agonistic effect of 9-hydroxycorynantheidine on μ-opioid receptor in the guinea-pig ileum

Kenjiro Matsumoto, Hiromitsu Takayama, Hayato Ishikawa, Norio Aimi, Dhavadee Ponglux, Kazuo Watanabe, Syunji Horie

Journal:

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

15

Two New Iridoids from the Leaves of Gelsemium elegans Benth. in Thailand

Takayama, Hiromitsu, Morohoshi, Yuhko, Kitajima, Mariko, Aimi, Norio, Wongseripipatana, Sumphan, Ponglux, Dhavadee, Sakai, Shin-Ichiro

Journal:

Natural Product Letters

Year:

1994

Language:

english

File:

PDF, 307 KB

english, 1994

16

Structures of Us-7 and Us-8: a new type of oxindole alkaloids isolated from Uncaria attenuata Korth

Aimi, Norio, Shimizu, Toshikazu, Sada, Hiroyuki, Takayama, Hiromitsu, Sakai, Shin-ichiro, Wongseripipatana, Sumphan, Ponglux, Dhavadee

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1997

Language:

english

File:

PDF, 241 KB

english, 1997

17

Indole Alkaloids of a Thai Medicinal Herb, Mitragyna speciosa, that has Opioid Agonistic Effect in Guinea-Pig Ileum

Horie, Syunji, Koyama, Fumi, Takayama, Hiromitsu, Ishikawa, Hayato, Aimi, Norio, Ponglux, Dhavadee, Matsumoto, Kenjiro, Murayama, Toshihiko

Journal:

Year:

2005

Language:

english

File:

PDF, 163 KB

english, 2005

18

Alkaloids from Uncaria quadrangularis

Tantivatana, Payom, Ponglux, Dhavadee, Jirawongse, V., Silpvisavanont, Yupa

Journal:

Year:

1979

Language:

english

File:

PDF, 214 KB

english, 1979

19

A new indole alkaloid, 14.ALPHA.-hydroxyrauniticine : Structure revision and partial synthesis.

YAMANAKA, ETSUJI, MARUTA, ETSUKO, KASAMATSU, SATOE, AIMI, NORIO, SAKAI, SHIN-ICHIRO, PONGLUX, DHAVADEE, WONGSERIPIPATANA, SUMPHAN, SUPAVITA, TANOMJIT, PHILLIPSON, J. DAVID

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 890 KB

1986

20

Indole alkaloids isolated from Gelsemium elegans (Thailand): 19-(Z)-akuammidine, 16-epi-voacarpine, 19-hydroxydihydrogelsevirine, and the revised structure of koumidine.

Sakai, Shin-ichiro, Wongseripipatana, Sumphan, Ponglux, Dhavadee, Yokota, Masaki, Ogata, Koreharu, Takayama, Hiromitsu, Aimi, Norio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 420 KB

english, 1987

21

Structure and synthesis of two new types of oxindole alkaloids found from Uncaria salaccensis.

PONGLUX, Dhavadee, WONGSERIPIPATANA, Sumphan, AIMI, Norio, NISHIMURA, Masashi, ISHIKAWA, Midori, SADA, Hiroyuki, HAGINIWA, Joju, SAKAI, Shin-ichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 393 KB

1990

22

Structures of two new bitter principles isolated from a Thai Medicinal Plant, Vernonia Extensa D.C..

PONGLUX, Dhavadee, WONGSERIPIPATANA, Sumphan, AIMI, Norio, OYA, Naoko, HOSOKAWA, Hajime, HAGINIWA, Joju, SAKAI, Shin-ichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1992

File:

PDF, 501 KB

1992

23

A Nuclear Magnetic Resonance Study on the Eleven Stereoisomers of Heteroyohimbine-Type Oxindole Alkaloids.

SEKI, Hiroko, TAKAYAMA, Hiromitsu, AIMI, Norio, SAKAI, Shin-ichiro, PONGLUX, Dhavadee

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1993

File:

PDF, 1.07 MB

1993

24

New Corymine-Related Indole Alkaloids from Hunteria zeylanica in Thailand.

SUBHADHIRASAKUL, Sanan, TAKAYAMA, Hiromitsu, MIYABE, Yuhko, AIMI, Norio, PONGLUX, Dhavadee, SAKAI, Shin-ichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 478 KB

1994

25

A New Class of Two Dimeric Indole Alkaloids, Coryzeylamine and Deformylcoryzeylamine, from the Leaves of Hunteria zeylanica in Thailand.

TAKAYAMA, Hiromitsu, SUBHADHIRASAKUL, Sanan, MIZUKI, Junko, KITAJIMA, Mariko, AIMI, Norio, PONGLUX, Dhavadee, SAKAI, Shin-ichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 545 KB

1994

26

Hunterioside, First Biose Bound Monoterpenoid Indole Alkaloid from Hunteria zeylanica.

SUBHADHIRASAKUL, Sanan, AIMI, Norio, TAKAYAMA, Hiromitsu, PONGLUX, Dhavadee, SAKAI, Shin-ichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 517 KB

1994

27

Novel Indole Alkaloids from the Leaves of Rauwolfia sumatrana JACK. in Thailand.

SUBHADHIRASAKUL, Sanan, TAKAYAMA, Hiromitsu, AIMI, Norio, PONGLUX, Dhavadee, SAKAI, Shin-ichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 723 KB

1994

28

Hunterioside B, a Disaccharide Carrying Monoterpenoid Indole Alkaloid, from Hunteria zeylanica

Aimi, Norio, Takayama, Hiromitsu, Subhadhirasakul, Sanan, Ohmori, Osamu, Kitajima, Mariko, Ponglux, Dhavadee

Journal:

Year:

1998

File:

PDF, 109 KB

1998

29

Hunterioside B, a Disaccharide Carrying Monoterpenoid Indole Alkaloid, from Hunteria zeylanica

Aimi, Norio, Takayama, Hiromitsu, Subhadhirasakul, Sanan, Ohmori, Osamu, Kitajima, Mariko, Ponglux, Dhavadee

Journal:

Year:

1998

Language:

english

File:

PDF, 109 KB

english, 1998

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